Malinga ndi kusungunuka kwa ma antioxidants, amatha kugawidwa m'magulu awiri: madzi{0}}soluble antioxidants ndi mafuta-soluble antioxidants. Madzi-mankhwala osungunuka osungunuka m'madzi amapezeka mu cytoplasmic matrix ndi plasma, pamene mafuta{4}}mankhwala osungunuka osungunuka amateteza mafuta a m'maselo kuti asawonongedwe. Mankhwalawa amapangidwa ndi biosynthesized m'thupi la munthu kapena amalowetsedwa kudzera muzakudya. Ma antioxidants osiyanasiyana amagawidwa m'madzi am'thupi ndi minofu m'magulu osiyanasiyana. Glutathione ndi coenzyme Q10 zimapezeka makamaka m'maselo, pomwe ma antioxidants ena monga uric acid amagawidwa kwambiri (onani tebulo ili m'munsimu kuti mudziwe zambiri). Ma antioxidants ena amapezeka m'magulu ena amthupi chifukwa cha zotsatira zake za antioxidant komanso ma virus ofunikira komanso zinthu zoyambitsa matenda.
Zosakaniza zina zimagwirizanitsa ndi chelate ndi zitsulo zosinthika kuti ziteteze zitsulo kuti zisapangitse kupanga ma radicals aulere m'maselo, motero amathandizira chitetezo cha antioxidant. Mfundo yofunika kwambiri mu njira yolimbana ndi -yoteteza oxidant imeneyi ndi yopatula ayoni ayironi kudzera mu coordination chelation, chifukwa ma ayoni ayironi ndiye chinsinsi cha ayironi{2}}yomangira ma protein monga transferrin ndi ferritin{3}} Selenium ndi zinc nthawi zambiri zimatengedwa ngati michere ya antioxidant. Zinthu ziwirizi zilibe antioxidant mphamvu koma zimatha kugwira ntchito ya ma enzyme ena a antioxidant.
